Xeomin San Diego

Neurotoxins are prescription medications injected into muscles and used to temporarily improve the appearance of moderate to severe frown lines between the eyebrows (glabellar lines) in adults. Aesthetic neurotoxins include botulinum toxin type A, a protein purified from the bacterium Clostridium botulinum.

State-of-the-Art Manufacturing Process.

We’ve selected this product because it is made through a unique precision manufacturing process that isolates the therapeutic component of the molecule and removes the complexing/unnecessary proteins that don’t play an active role in treatment. This provides for a uniquely purified neurotoxin. Studies have not been performed to determine whether the presence or absence of complexing/unnecessary proteins has a long-term effect on safety or efficacy.

When you squint or frown, the muscles between your eyebrows contract, causing the skin to furrow and fold. Over time, as your skin ages and loses some of its elasticity, these repeated contractions can cause persistent frown lines. Botulinum toxin type A – the active ingredient in neurotoxin products – acts on nerve endings in muscles to prevent muscle fibers from contracting. By reducing these contractions, This allows us to temporarily reduce/eliminate the lines between your eyebrows.

The neurotoxin (NT) we prefer has been proven effective in two randomized, double-blind, multicenter, placebo-controlled clinical trials of 547 healthy, adult patients. The average age of patients in the study was 46 years. Patients received 20 Units of NT and were classified as responders if they had a 2-grade improvement on a 4-point scale as assessed by the physician and patient. Using these criteria, treatment success was higher with the NT than placebo on Day 30 in both studies (60% and 48% vs. 0% for placebo in both studies). 

If you are an adult with moderate to severe glabellar lines, use of a NT may be right for you. Talk to your doctor to discuss the benefits and risks of treatment. Do not use if you are allergic to botulinum toxin or any of the other ingredients in the product. You should also not use a NT if you have had an allergic reaction to any other botulinum toxin product or have a skin infection at the planned injection site.

Before receiving treatment with a neurotoxin, you should tell your doctor about all of your medical conditions, including whether you have a disease that affects your muscles and nerves, have allergies to any botulinum toxin product, or have experienced any side effect from any other botulinum toxin in the past. In addition, tell your doctor about your medical history and all the medicines you take, including prescription and nonprescription medicines, vitamins, and herbal supplements. Especially tell your doctor if you have received any other botulinum toxin product in the last four months or in the past. Be sure your doctor knows exactly which product(s) you received and when you received them.

During treatment, which usually takes about 10-20 minutes, your doctor will inject the product into the muscles in your forehead that cause frown lines between your eyebrows. No anesthesia is required; however, your physician may use a topical anesthetic or cold pack to reduce any discomfort.

You may begin to see visible smoothing as early as 3-4 days after injection. The median first onset of effect was less than a week. The maximum effect occurred at 30 days. The typical duration of effect was up to 3 months in clinical trials but may last significantly longer or shorter in individual patients.

Use of a neurotoxin may cause serious side effects, including allergic reactions. Symptoms of an allergic reaction to may include: itching, rash, redness, swelling, wheezing, asthma symptoms, or dizziness or feeling faint. Tell your doctor or seek medical help right away if you have wheezing, experience other asthma symptoms, or if you become dizzy or faint. In clinical trials for the treatment of frown lines between the eyebrows, headache was the most common side effect. Neurotoxin use may cause loss of strength or general muscle weakness, blurred vision, or drooping eyelids within hours to weeks of injection. If this happens, do not drive a car, operate machinery, or do other dangerous activities. Tell your doctor if you have any side effect that bothers you or that does not subside. These are not all of the possible side effects of neurotoxin injection.